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Subject Syllabus

AL803 (B) - Bio Informatics

AIML · Semester 8

Course Modules

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Introduction to bioinformatics Objectives of bioinformatics Basic chemistry of nucleic acids Structure of DNA & RNA Genes, structure of bacterial chromosome Cloning methodology Data maintenance and Integrity Tasks

Types of databases Nucleotide sequence databases Protein sequence databases Protein structure databases Normalization Data cleaning and transformation Protein folding, protein function, protein purification and characterization Introduction to Java clients, CORBA Using MYSQL Feature Extraction

Introduction to sequence analysis Models for sequence analysis Methods of optimal alignment Tools for sequence alignment Dynamics Programming Heuristic Methods Multiple sequences Alignment

Cracking the Genome Biological decoder ring Finding genes through mathematics & learning Genes prediction tools Gene Mapping, Application of Mapping Modes of Gene Expression data Mining the Gene Expression Data

Proteome analysis Tools for proteome analysis Genetic networks Network properties and analysis Complete pathway simulation: E-cell Genomic analysis for DNA & Protein sequences Strategies and options for similarity search Flowcharts for protein structure prediction